最新的预防外科手术部位感染指南（surgical site infections），强调外科预防手术部位感染，预防性应用抗生素应该是：手术切皮前1个小时内用药，切口缝合后就应该停药，出手术室以后再用药有害无益。Appropriateness includes (1) correct antibiotic for specific surgery, (2) correct antibiotic dose, (3) administration start time within 1 hour of incision (2 hours allowed for vancomycin and fluoroquinolones), and (4) discontinuation of the agent after skin closure. http://t.cn/A6NTdhbw